Combining certain types of
blood pressure medications can be risky, Health Canada is warning doctors and
patients.The regulator said Tuesday
that recent studies show any combination of aliskiren, a renin inhibitor, and
two other classes of drugs, angiotensin-converting enzyme (ACE) inhibitors or
angiotensin receptor blockers (ARB), can be risky.
BP Checking |
Any combination of three
types of blood pressure medicines increases the risk of low blood pressure and
other health problems, Health Canada says. (Eric Risberg/Associated Press)"Recent studies have
demonstrated that any combination of aliskiren, ACEIs or ARBs increases the
risks of hypotension (low blood pressure), hyperglycemia (high levels of
potassium in the blood) and kidney problems," Health Canada said
in a notice to health professionals and patients.
The department added
that aliskiren should not be taken in combination with ACEIs or with ARBs
in patients with diabetes or kidney disease because of their additional risks
of stroke and syncope or fainting.
Drug makers are updating
product labels to reflect the new recommendations, Health Canada said.
A list of the products containing
these medications can be found on Health Canada's website.
People should not stop
treatment for high blood pressure without consulting their doctor or healthcare
professional.
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